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The Chandran Lab
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  • news & media/
  • research/
  • team/
  • publications/
  • find us/
  • positions/
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The Chandran Lab

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The Chandran Lab
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October 16, 2022

Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2→

October 16, 2022/ Kartik Chandran
Cell-impermeable staurosporine analog targets extracellular kinases to inhibit HSV and SARS-CoV-2

Cheshenko N et al, Commun Biol 2022

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October 16, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
July 13, 2022

Genomic surveillance of SARS-CoV-2 during the first year of the pandemic in the Bronx enabled clinical and epidemiological inference→

July 13, 2022/ Kartik Chandran
Genomic surveillance of SARS-CoV-2 during the first year of the pandemic in the Bronx enabled clinical and epidemiological inference

Fels JM et al, Cold Spring Harb Mol Case Stud 2022

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July 13, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
June 09, 2022

A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice→

June 09, 2022/ Kartik Chandran
A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice

Malonis RJ et al, PLoS Pathog 2022

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June 09, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
March 30, 2022

Induction of SARS-CoV-2 neutralizing antibodies by CoronaVac and BNT162b2 vaccines in naïve and previously infected individuals→

March 30, 2022/ Kartik Chandran
Induction of SARS-CoV-2 neutralizing antibodies by CoronaVac and BNT162b2 vaccines in naïve and previously infected individuals

Muena N et al, EBiomedicine 2022

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March 30, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
March 16, 2022

Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses→

March 16, 2022/ Kartik Chandran
Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses

Mittler E et al, Science Transl Med 2022

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March 16, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
February 09, 2022

Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies→

February 09, 2022/ Kartik Chandran
Genotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies

Haslwanter D et al, Cell Host Microbe 2022

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February 09, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
February 01, 2022

Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients: A Randomized Clinical Trial→

February 01, 2022/ Kartik Chandran
Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients: A Randomized Clinical Trial

Ortigoza MB et al, JAMA Internal Med 2022

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February 01, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
January 18, 2022

Longitudinally monitored immune biomarkers predict the timing of COVID-19 outcomes→

January 18, 2022/ Kartik Chandran
Longitudinally monitored immune biomarkers predict the timing of COVID-19 outcomes

Lasso G et al, PLoS Comput Biol 2022

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January 18, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
January 07, 2022

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies→

January 07, 2022/ Kartik Chandran
Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies

Mishra AK et al, Science 2022

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January 07, 2022/ Kartik Chandran/ Comment /Source
researchpage, 2022
November 25, 2021

Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response→

November 25, 2021/ Kartik Chandran
Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response

Herman JD et al, Nature Communications 2022

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November 25, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
October 14, 2021

Two Distinct Lysosomal Targeting Strategies Afford Trojan Horse Antibodies With Pan-Filovirus Activity→

October 14, 2021/ Kartik Chandran
Two Distinct Lysosomal Targeting Strategies Afford Trojan Horse Antibodies With Pan-Filovirus Activity

Wirchnianski AS et al, Front Immunol 2021

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October 14, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
October 05, 2021

A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants→

October 05, 2021/ Kartik Chandran
A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants

Haslwanter D & Dieterle ME et al, mBio 2021

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October 05, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
September 14, 2021

Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses→

September 14, 2021/ Kartik Chandran
Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses

Malonis RJ et al, Proc Natl Acad Sci 2021

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September 14, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
August 01, 2021

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Qualitative Immunoglobulin G Assays: The Value of Numeric Reporting→

August 01, 2021/ Kartik Chandran
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Qualitative Immunoglobulin G Assays: The Value of Numeric Reporting

Forest SK et al, Arch Pathol Lab Med 2021

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August 01, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
July 12, 2021

Generation of plasma cells and CD27 - IgD - B cells during hantavirus infection is associated with distinct pathological findings→

July 12, 2021/ Kartik Chandran
Generation of plasma cells and CD27 - IgD - B cells during hantavirus infection is associated with distinct pathological findings

Kerkman PF et al, Clin Transl Immunol 2021

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July 12, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
July 06, 2021

Genetic depletion studies inform receptor usage by virulent hantaviruses in human endothelial cells→

July 06, 2021/ Kartik Chandran
Genetic depletion studies inform receptor usage by virulent hantaviruses in human endothelial cells

Dieterle ME et al, eLife 2021

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July 06, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
June 24, 2021

Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever→

June 24, 2021/ Kartik Chandran
Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever

Fels JM et al, Cell 2021

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June 24, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
April 30, 2021

MAVERICC: Marker-free Vaccinia Virus Engineering of Recombinants through in vitro CRISPR/Cas9 Cleavage→

April 30, 2021/ Kartik Chandran
MAVERICC: Marker-free Vaccinia Virus Engineering of Recombinants through in vitro CRISPR/Cas9 Cleavage

Laudermilch E et al, J Mol Biol 2021

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April 30, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
April 05, 2021

Single-Dilution COVID-19 Antibody Test with Qualitative and Quantitative Readouts→

April 05, 2021/ Kartik Chandran
Single-Dilution COVID-19 Antibody Test with Qualitative and Quantitative Readouts

Bortz RH III et al, mSphere 2021

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April 05, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
March 18, 2021

The shape of pleomorphic virions determines resistance to cell-entry pressure→

March 18, 2021/ Kartik Chandran
The shape of pleomorphic virions determines resistance to cell-entry pressure

Li T et al, Nat Microbiol 2021

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March 18, 2021/ Kartik Chandran/ Comment /Source
researchpage, 2021
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