The Chandran Lab
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The Chandran Lab
  • home/
  • news & media/
  • research/
  • team/
  • publications/
  • find us/
  • positions/
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The Chandran Lab

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The Chandran Lab
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January 20, 2016

Cysteine cathepsin inhibitors as anti-Ebola agents→

January 20, 2016/ Kartik Chandran
Cysteine cathepsin inhibitors as anti-Ebola agents

van der Linden W et al, ACS Infect Dis 2016

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January 20, 2016/ Kartik Chandran/ Comment /Source
2016-2017, cathepsin, filovirus, antivirals, Ebola virus, researchpage, 2016
April 01, 2015

Distinct cathepsins control necrotic cell death mediated by pyroptosis inducers and lysosome-destabilizing agents→

April 01, 2015/ Kartik Chandran
Distinct cathepsins control necrotic cell death mediated by pyroptosis inducers and lysosome-destabilizing agents

Brojatsch J et al, Cell Cycle 2015

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April 01, 2015/ Kartik Chandran/ Comment /Source
cathepsin, cell death, necroptosis, 2014–2015, 2015
June 03, 2014

A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants→

June 03, 2014/ Kartik Chandran
A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants

Jacobson J et al, PLoS One 2014

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June 03, 2014/ Kartik Chandran/ Comment /Source
2014–2015, cathepsin, cell death, necroptosis, 2014
June 15, 2013

Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death→

June 15, 2013/ Kartik Chandran
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death

Lima H, Jacobson LS et al, Cell Cycle 2013

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June 15, 2013/ Kartik Chandran/ Comment /Source
2012–2013, cathepsin, cell death, necroptosis, 2013
January 07, 2013

Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants→

January 07, 2013/ Kartik Chandran
Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants

Jacobson LS et al, J Biol Chem 2013

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January 07, 2013/ Kartik Chandran/ Comment /Source
2012–2013, cathepsin, cell death, necroptosis, 2013
January 11, 2012

Filoviruses require endosomal cysteine proteases for entry but display distinct protease preferences→

January 11, 2012/ Kartik Chandran
Filoviruses require endosomal cysteine proteases for entry but display distinct protease preferences

Misasi J, Chandran K et al, J Virol 2012

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January 11, 2012/ Kartik Chandran/ 1 Comment /Source
filovirus, host factors, cathepsin, Ebola virus, 2012–2013, researchpage, 2011
January 01, 2010

A forward genetic strategy reveals destabilizing mutations in the ebolavirus glycoprotein that alter its protease dependence during cell entry→

January 01, 2010/ Kartik Chandran
A forward genetic strategy reveals destabilizing mutations in the ebolavirus glycoprotein that alter its protease dependence during cell entry

Wong AC et al, J Virol 2010

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January 01, 2010/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, cathepsin, host factors, membrane fusion, 2010–2011, researchpage, 2010

© 2015, Kartik Chandran Laboratory