The Chandran Lab
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The Chandran Lab
  • home/
  • news & media/
  • research/
  • team/
  • publications/
  • find us/
  • positions/
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The Chandran Lab

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The Chandran Lab
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December 23, 2015

Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats→

December 23, 2015/ Kartik Chandran
Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats

Ng M, Ndungo E, Kaczmarek ME et al, eLife 2015

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December 23, 2015/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, host factors, receptors, NPC1, researchpage, 2014–2015, 2015
July 22, 2015

Novel small molecule entry inhibitors of Ebola virus→

July 22, 2015/ Kartik Chandran
Novel small molecule entry inhibitors of Ebola virus

Basu A et al, J Infect Dis 2015

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July 22, 2015/ Kartik Chandran/ Comment /Source
Ebola virus, therapeutics, filovirus, GP, 2014–2015, antivirals, 2015
June 03, 2015

Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion→

June 03, 2015/ Kartik Chandran
Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion

Kleinfelter LM, Jangra RK, Jae LT et al, MBio 2015

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June 03, 2015/ Kartik Chandran/ 1 Comment /Source
hantavirus, cholesterol, membrane fusion, host factors, genetic screen, 2014–2015, researchpage, kleinfelter2015, 2015
May 26, 2015

Niemann-Pick C1 Is essential for ebolavirus replication and pathogenesis in vivo→

May 26, 2015/ Kartik Chandran
Niemann-Pick C1 Is essential for ebolavirus replication and pathogenesis in vivo

Herbert AS et al, MBio 2015

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May 26, 2015/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, NPC1, pathogenesis, host, animal model, receptors, host factors, therapeutics, 2014–2015, antivirals, researchpage, 2015
April 01, 2015

Distinct cathepsins control necrotic cell death mediated by pyroptosis inducers and lysosome-destabilizing agents→

April 01, 2015/ Kartik Chandran
Distinct cathepsins control necrotic cell death mediated by pyroptosis inducers and lysosome-destabilizing agents

Brojatsch J et al, Cell Cycle 2015

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April 01, 2015/ Kartik Chandran/ Comment /Source
cathepsin, cell death, necroptosis, 2014–2015, 2015
October 11, 2014

Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1→

October 11, 2014/ Kartik Chandran
Cell entry by a novel European filovirus requires host endosomal cysteine proteases and Niemann-Pick C1

Ng M et al, Virology 2014

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October 11, 2014/ Kartik Chandran/ Comment /Source
Ebola virus, Lloviu virus, NPC1, host factors, 2014–2015, filovirus, receptors, researchpage, 2014
August 20, 2014

Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge→

August 20, 2014/ Kartik Chandran
Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge

Chen G, Koellhoffer JF, Zak SE et al, ACS Chem Biol 2014

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August 20, 2014/ Kartik Chandran/ Comment /Source
therapeutics, antibody, GP, pathogenesis, animal model, 2014–2015, filovirus, 2014
June 03, 2014

A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants→

June 03, 2014/ Kartik Chandran
A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants

Jacobson J et al, PLoS One 2014

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June 03, 2014/ Kartik Chandran/ Comment /Source
2014–2015, cathepsin, cell death, necroptosis, 2014
January 28, 2014

Comprehensive functional analysis of N-linked glycans on Ebola virus GP1→

January 28, 2014/ Kartik Chandran
Comprehensive functional analysis of N-linked glycans on Ebola virus GP1

Lennemann NJ et al, MBio 2014

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January 28, 2014/ Kartik Chandran/ Comment /Source
GP, vaccine, 2014–2015, filovirus, 2014
December 12, 2013

Structural characterization of the glycoprotein GP2 core domain from the CAS virus, a novel arenavirus-like species→

December 12, 2013/ Kartik Chandran
Structural characterization of the glycoprotein GP2 core domain from the CAS virus, a novel arenavirus-like species

Koellhoffer JF, Dai Z et al, J Mol Biol 2014

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December 12, 2013/ Kartik Chandran/ Comment /Source
arenavirus, CASV, GP, 2014–2015, membrane fusion, 2014

© 2015, Kartik Chandran Laboratory