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The Chandran Lab
  • home/
  • news & media/
  • research/
  • team/
  • publications/
  • find us/
  • positions/
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The Chandran Lab

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The Chandran Lab
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September 08, 2016

A “Trojan horse” bispecific antibody strategy for broad protection against ebolaviruses→

September 08, 2016/ Kartik Chandran
A “Trojan horse” bispecific antibody strategy for broad protection against ebolaviruses

Wec AZ et al, Science 2016

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September 08, 2016/ Kartik Chandran/ Comment /Source
2016-2017, Ebola virus, filovirus, therapeutics, antibody, host factors, NPC1, antivirals, researchpage, 2016
January 20, 2016

Cysteine cathepsin inhibitors as anti-Ebola agents→

January 20, 2016/ Kartik Chandran
Cysteine cathepsin inhibitors as anti-Ebola agents

van der Linden W et al, ACS Infect Dis 2016

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January 20, 2016/ Kartik Chandran/ Comment /Source
2016-2017, cathepsin, filovirus, antivirals, Ebola virus, researchpage, 2016
July 22, 2015

Novel small molecule entry inhibitors of Ebola virus→

July 22, 2015/ Kartik Chandran
Novel small molecule entry inhibitors of Ebola virus

Basu A et al, J Infect Dis 2015

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July 22, 2015/ Kartik Chandran/ Comment /Source
Ebola virus, therapeutics, filovirus, GP, 2014–2015, antivirals, 2015
May 26, 2015

Niemann-Pick C1 Is essential for ebolavirus replication and pathogenesis in vivo→

May 26, 2015/ Kartik Chandran
Niemann-Pick C1 Is essential for ebolavirus replication and pathogenesis in vivo

Herbert AS et al, MBio 2015

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May 26, 2015/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, NPC1, pathogenesis, host, animal model, receptors, host factors, therapeutics, 2014–2015, antivirals, researchpage, 2015
August 02, 2013

C-Peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: Effects of conjugation to cholesterol and side chain-side chain cross linking→

August 02, 2013/ Kartik Chandran
C-Peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: Effects of conjugation to cholesterol and side chain-side chain cross linking

Higgins CD et al, Bioorg Med Chem Lett 2013

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August 02, 2013/ Kartik Chandran/ Comment /Source
filovirus, membrane fusion, antivirals
April 19, 2013

Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids→

April 19, 2013/ Kartik Chandran
Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids

Regula LK, Harris R et al, Biochemistry 2013

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April 19, 2013/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, membrane fusion, GP, 2012–2013, antivirals, 2013
May 06, 2011

Inhibition of Ebola virus entry by a C-peptide targeted to endosomes→

May 06, 2011/ Kartik Chandran
Inhibition of Ebola virus entry by a C-peptide targeted to endosomes

Miller EH, Harrison JS et al, J Biol Chem 2011

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May 06, 2011/ Kartik Chandran/ Comment /Source
filovirus, Ebola virus, membrane fusion, antivirals, 2010–2011, researchpage, 2011

© 2015, Kartik Chandran Laboratory