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The Chandran Lab
  • home/
  • news & media/
  • research/
  • team/
  • publications/
  • find us/
  • positions/
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The Chandran Lab

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The Chandran Lab
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June 15, 2013

Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death→

June 15, 2013/ Kartik Chandran
Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death

Lima H, Jacobson LS et al, Cell Cycle 2013

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June 15, 2013/ Kartik Chandran/ Comment /Source
2012–2013, cathepsin, cell death, necroptosis, 2013
April 19, 2013

Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids→

April 19, 2013/ Kartik Chandran
Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids

Regula LK, Harris R et al, Biochemistry 2013

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April 19, 2013/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, membrane fusion, GP, 2012–2013, antivirals, 2013
January 09, 2013

A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species and cell-type specific manner→

January 09, 2013/ Kartik Chandran
A mutation in the Ebola virus envelope glycoprotein restricts viral entry in a host species and cell-type specific manner

Martinez O et al, J Virol 2013

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January 09, 2013/ Kartik Chandran/ Comment /Source
2012–2013, filovirus, NPC1, host factors, receptors, 2013
January 07, 2013

Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants→

January 07, 2013/ Kartik Chandran
Cathepsin-mediated Necrosis Controls the Adaptive Immune Response by Th2 (T helper type 2)-associated Adjuvants

Jacobson LS et al, J Biol Chem 2013

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January 07, 2013/ Kartik Chandran/ Comment /Source
2012–2013, cathepsin, cell death, necroptosis, 2013
December 11, 2012

Endocytic pathways involved in filovirus entry: advances, implications and future directions→

December 11, 2012/ Kartik Chandran
Endocytic pathways involved in filovirus entry: advances, implications and future directions

Bhattacharyya S et al, Viruses 2012

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December 11, 2012/ Kartik Chandran/ Comment /Source
2012–2013, filovirus, host factors, receptors, review, 2012
October 30, 2012

Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the Ebola virus envelope glycoprotein→

October 30, 2012/ Kartik Chandran
Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the Ebola virus envelope glycoprotein

Koellhoffer JF, Chen G et al, Chembiochem 2012

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October 30, 2012/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, antibody, 2012–2013, researchpage, 2012
October 25, 2012

NPC1/NPC1-like1 Chimeras Define Sequences Critical for NPC1’s Function as a Filovirus Entry Receptor→

October 25, 2012/ Kartik Chandran
NPC1/NPC1-like1 Chimeras Define Sequences Critical for NPC1’s Function as a Filovirus Entry Receptor

Krishnan A et al, Viruses 2012

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October 25, 2012/ Kartik Chandran/ Comment /Source
2012–2013, receptors, NPC1, filovirus, Ebola virus, host factors, researchpage, 2012
August 30, 2012

Crystal Structure of the Marburg virus GP2 core domain in its post-fusion conformation→

August 30, 2012/ Kartik Chandran
Crystal Structure of the Marburg virus GP2 core domain in its post-fusion conformation

Koellhoffer JF et al, Biochemistry 2012

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August 30, 2012/ Kartik Chandran/ 1 Comment /Source
2012–2013, filovirus, Ebola virus, membrane fusion, 2012
April 05, 2012

Structural basis for differential neutralization of ebolaviruses→

April 05, 2012/ Kartik Chandran
Structural basis for differential neutralization of ebolaviruses

Bale S, Dias JM et al, Viruses 2012

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April 05, 2012/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, antibody, 2012–2013, 2012
March 23, 2012

Filovirus entry into cells—new insights→

March 23, 2012/ Kartik Chandran
Filovirus entry into cells—new insights

Miller and Chandran, Curr Opin Virol 2012

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March 23, 2012/ Kartik Chandran/ Comment /Source
2012–2013, receptors, host factors, review, 2012
March 06, 2012

Ebola virus entry requires the host-programmed recognition of an intracellular receptor→

March 06, 2012/ Kartik Chandran
Ebola virus entry requires the host-programmed recognition of an intracellular receptor

Miller EH, Obernosterer G, Raaben M, Herbert AS et al, EMBO J 2012

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March 06, 2012/ Kartik Chandran/ Comment /Source
2012–2013, Ebola virus, filovirus, host factors, receptors, NPC1, 2012
February 27, 2012

Marburg Virus Glycoprotein GP2: pH-Dependent Stability of the Ectodomain Alpha-Helical Bundle→

February 27, 2012/ Kartik Chandran
Marburg Virus Glycoprotein GP2: pH-Dependent Stability of the Ectodomain Alpha-Helical Bundle

Harrison JS et al, Biochemistry 2012

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February 27, 2012/ Kartik Chandran/ 1 Comment /Source
filovirus, Ebola virus, membrane fusion, 2012–2013, 2012
January 11, 2012

Filoviruses require endosomal cysteine proteases for entry but display distinct protease preferences→

January 11, 2012/ Kartik Chandran
Filoviruses require endosomal cysteine proteases for entry but display distinct protease preferences

Misasi J, Chandran K et al, J Virol 2012

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January 11, 2012/ Kartik Chandran/ 1 Comment /Source
filovirus, host factors, cathepsin, Ebola virus, 2012–2013, researchpage, 2011

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