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  • news & media/
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February 09, 2016

Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway→

February 09, 2016/ Kartik Chandran
Direct Visualization of Ebola Virus Fusion Triggering in the Endocytic Pathway

Spence JS et al, mBio 2016

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February 09, 2016/ Kartik Chandran/ Comment /Source
2016-2017, Ebola virus, membrane fusion, GP, filovirus, host factors, researchpage, 2016
January 29, 2016

Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses→

January 29, 2016/ Kartik Chandran
Bispecific Antibody Affords Complete Post-Exposure Protection of Mice from Both Ebola (Zaire) and Sudan Viruses

Frei JC, Nyakatura EK, et al, Sci Rep 2016

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January 29, 2016/ Kartik Chandran/ Comment /Source
2016-2017, GP, antibody, therapeutics, Ebola virus, filovirus, 2016
July 22, 2015

Novel small molecule entry inhibitors of Ebola virus→

July 22, 2015/ Kartik Chandran
Novel small molecule entry inhibitors of Ebola virus

Basu A et al, J Infect Dis 2015

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July 22, 2015/ Kartik Chandran/ Comment /Source
Ebola virus, therapeutics, filovirus, GP, 2014–2015, antivirals, 2015
August 20, 2014

Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge→

August 20, 2014/ Kartik Chandran
Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge

Chen G, Koellhoffer JF, Zak SE et al, ACS Chem Biol 2014

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August 20, 2014/ Kartik Chandran/ Comment /Source
therapeutics, antibody, GP, pathogenesis, animal model, 2014–2015, filovirus, 2014
January 28, 2014

Comprehensive functional analysis of N-linked glycans on Ebola virus GP1→

January 28, 2014/ Kartik Chandran
Comprehensive functional analysis of N-linked glycans on Ebola virus GP1

Lennemann NJ et al, MBio 2014

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January 28, 2014/ Kartik Chandran/ Comment /Source
GP, vaccine, 2014–2015, filovirus, 2014
December 12, 2013

Structural characterization of the glycoprotein GP2 core domain from the CAS virus, a novel arenavirus-like species→

December 12, 2013/ Kartik Chandran
Structural characterization of the glycoprotein GP2 core domain from the CAS virus, a novel arenavirus-like species

Koellhoffer JF, Dai Z et al, J Mol Biol 2014

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December 12, 2013/ Kartik Chandran/ Comment /Source
arenavirus, CASV, GP, 2014–2015, membrane fusion, 2014
April 19, 2013

Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids→

April 19, 2013/ Kartik Chandran
Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids

Regula LK, Harris R et al, Biochemistry 2013

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April 19, 2013/ Kartik Chandran/ Comment /Source
Ebola virus, filovirus, membrane fusion, GP, 2012–2013, antivirals, 2013

© 2015, Kartik Chandran Laboratory